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All about COVID19 - An initiative from WhiteCoats that brings together updates from top curated resources exclusively for healthcare professionals

Immunological pathways dysregulated in COVID-19 largely overlap with multiple sclerosis (MS) pathogenetic mechanisms. In COVID-19 brains, choroid barrier cells and glia limitans release chemokines toward brain parenchyma and promote complement activation, fueling neuroinflammation and neural damage. A similar mechanism is described in MS, where an activated choroid epithelium in response to peripheral inflammation activates pathogenic B and T lymphocytes. In ...

A retrospective cohort study including 60 pediatric patients hospitalized for asthma was conducted to evaluate the impact of COVID-19 infection on childhood asthma. The patient’s age was between 2-12 years, 58% were male and 10% were diagnosed with COVID-19. The patients were divided into two groups: asthma with COVID-19 and without COVID-19 to study the clinical and laboratory characteristics and ...

Statins including lovastatin have anti-viral, anti-inflammatory, anti-thrombotic, and immunomodulatory features which might play a potential role in treatment and prevention of SARS-CoV-2. Statins alleviate the effects of myocardial damage and thrombosis related to the COVID-19 infection. A case-control study was conducted to evaluate the protective effects of lovastatin in ICU patients with COVID-19. The study included 284 COVID-19 ICU admitted ...

An increased Intestinal fatty-acid binding protein (I-FABP) level in urine indicates enterocyte cell damage. A prospective cohort study with 283 SARS-CoV-2 inpatients (survivors and non-survivors patients) and healthy volunteers was conducted to investigate the role of I-FABP as a predictor of disease severity and poor prognosis.. Venous blood and urine samples were collected at admission, and on 7th and 14th ...

Some stem cells release molecules that reduce viral replication and have the ability to reset the innate and adaptive immune systems from an inflammatory state to a repair state. Molecules released from the stem cells provide therapeutic benefits by fighting viral infections and the “cytokine storm” observed in COVID-19. Stem cells release molecules act in two ways, first by inhibiting ...

It is particularly important that a person with type 2 diabetes receives a COVID-19 vaccination. This is because they are at an increased risk of serious complications if they acquire the virus and go on to develop the disease. There are several vaccines available, all of which are safe for people with type 2 diabetes. The Centers for Disease Control ...