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All about COVID19 - An initiative from WhiteCoats that brings together updates from top curated resources exclusively for healthcare professionals

A cross-sectional study was carried out to assess the possible effect of SAR-CoV-2 infection on thyroid function. The study included 45 COVID-19 patients and 45 apparently healthy uninfected controls. The mean age of COVID-19 patients was 35.31±12.44 years, while uninfected controls had a mean age of 38.38 ± 8.08 years. 75.6% were males and 24.4% were females in the COVID-19 ...

Immunological pathways dysregulated in COVID-19 largely overlap with multiple sclerosis (MS) pathogenetic mechanisms. In COVID-19 brains, choroid barrier cells and glia limitans release chemokines toward brain parenchyma and promote complement activation, fueling neuroinflammation and neural damage. A similar mechanism is described in MS, where an activated choroid epithelium in response to peripheral inflammation activates pathogenic B and T lymphocytes. In ...

Both Hepatitis B virus (HBV) and SARS-CoV-2 can cause liver damage and hence it is important to understand the impact of HBV on SARS-CoV-2 infected patients. A large-scale, population-based, nationwide cohort study was conducted to measure the potential associations between CHB and the use of antiviral therapy with SARS-CoV-2 infection rates. A total of 204,418 patients were included with 7,723 ...

A study published in the journal BMJ Nutrition Prevention & Health revealed that taking multivitamins, probiotics, omega-3 or vitamin D supplements may lessen the risk of testing positive for COVID-19 infection. But taking any vitamin C, zinc, or garlic supplements wasn’t associated with a lower risk of testing positive for the virus, the findings show. There have been plenty of ...

A retrospective cohort study including 60 pediatric patients hospitalized for asthma was conducted to evaluate the impact of COVID-19 infection on childhood asthma. The patient’s age was between 2-12 years, 58% were male and 10% were diagnosed with COVID-19. The patients were divided into two groups: asthma with COVID-19 and without COVID-19 to study the clinical and laboratory characteristics and ...

There is an association between low zinc levels and the severity of acute respiratory distress syndrome (ARDS) in COVID-19 people. Artificial nutrition such as parenteral nutrition (PN) or enteral nutrition may be needed to avoid malnutrition. Low serum zinc and copper levels have been observed among ICU patients, whereas patients with high serum concentrations have significantly low mortality rates. A ...

Fibrinogen and albumin are routinely used parameters in COVID-19. High fibrinogen levels and low albumin levels are associated with the severity of COVID-19 disease. Moreover, the fibrinogen to albumin ratio (FAR) level is known to be a better marker in cases of coagulopathy. A retrospective study was conducted to analyse the clinical benefits of FAR in COVID-19. 590 COVID-19 patients ...

Statins including lovastatin have anti-viral, anti-inflammatory, anti-thrombotic, and immunomodulatory features which might play a potential role in treatment and prevention of SARS-CoV-2. Statins alleviate the effects of myocardial damage and thrombosis related to the COVID-19 infection. A case-control study was conducted to evaluate the protective effects of lovastatin in ICU patients with COVID-19. The study included 284 COVID-19 ICU admitted ...

An increased Intestinal fatty-acid binding protein (I-FABP) level in urine indicates enterocyte cell damage. A prospective cohort study with 283 SARS-CoV-2 inpatients (survivors and non-survivors patients) and healthy volunteers was conducted to investigate the role of I-FABP as a predictor of disease severity and poor prognosis.. Venous blood and urine samples were collected at admission, and on 7th and 14th ...

Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious and potentially life-threatening illness exhibited in COVID-19 children. It affects the majority of male children and occurs 2-4 weeks after SARS-CoV-2 infection. Patients with MIS-C have elevated biomarkers associated with vascular inflammation and damage. 70-90% of children with MIS-C show symptoms like fever, abdominal pain, vomiting, and diarrhea. Hematologic abnormalities are ...