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All about COVID19 - An initiative from WhiteCoats that brings together updates from top curated resources exclusively for healthcare professionals

A cross-sectional study was carried out to assess the possible effect of SAR-CoV-2 infection on thyroid function. The study included 45 COVID-19 patients and 45 apparently healthy uninfected controls. The mean age of COVID-19 patients was 35.31±12.44 years, while uninfected controls had a mean age of 38.38 ± 8.08 years. 75.6% were males and 24.4% were females in the COVID-19 ...

Both Hepatitis B virus (HBV) and SARS-CoV-2 can cause liver damage and hence it is important to understand the impact of HBV on SARS-CoV-2 infected patients. A large-scale, population-based, nationwide cohort study was conducted to measure the potential associations between CHB and the use of antiviral therapy with SARS-CoV-2 infection rates. A total of 204,418 patients were included with 7,723 ...

A study published in the journal BMJ Nutrition Prevention & Health revealed that taking multivitamins, probiotics, omega-3 or vitamin D supplements may lessen the risk of testing positive for COVID-19 infection. But taking any vitamin C, zinc, or garlic supplements wasn’t associated with a lower risk of testing positive for the virus, the findings show. There have been plenty of ...

There is an association between low zinc levels and the severity of acute respiratory distress syndrome (ARDS) in COVID-19 people. Artificial nutrition such as parenteral nutrition (PN) or enteral nutrition may be needed to avoid malnutrition. Low serum zinc and copper levels have been observed among ICU patients, whereas patients with high serum concentrations have significantly low mortality rates. A ...

Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious and potentially life-threatening illness exhibited in COVID-19 children. It affects the majority of male children and occurs 2-4 weeks after SARS-CoV-2 infection. Patients with MIS-C have elevated biomarkers associated with vascular inflammation and damage. 70-90% of children with MIS-C show symptoms like fever, abdominal pain, vomiting, and diarrhea. Hematologic abnormalities are ...

An observational study with a case-control design was conducted to analyze the prevalence of cerebral venous thrombosis (CVT) in adenovirus vector-based COVID19 vaccine recipients. All published cases and case series between March 01 and April 30, 2021, were screened, and specific reports from the United States Centers for Disease Control and Prevention and the European Medicines Agency providing patient-level data ...

Low dose radiation is effective against viral pneumonia and hypothetically found to suppress the cytokine release syndrome. Low-dose radiation has several advantages as compared to the current drugs and medicines for COVID-19. Several studies were proposed and conducted to study the impact of Low dose radiation therapy (LDRT) with a dose of 300 mGy or less on systemic immune function ...

Multiple studies are carried out to explore the benefits of antiviral drugs, especially hepatitis C virus direct-acting antivirals (HCV DAAs) to treat COVID-19. This study was conducted to evaluate the anti-SARS-CoV-2 effects of asunaprevir (a protease inhibitor), daclatasvir (an NS5A inhibitor) and sofosbuvir (an RNA polymerase inhibitor). Vero E6, Calu-3, Huh7.5, and HEK293T cell lines were used for testing the ...

Higher levels of ACE2 association in certain comorbidities explain its association with the severity of COVID-19. It has been demonstrated that ACE2 is highly expressed in the esophagus of patients with Barrett's esophagus (BE) and that the acidic pH associated with this condition is a key inducer of ACE2 expression. In-vitro analyses have depicted that in primary monocyte culture, ACE2 ...

Clarithromycin (CAM) has diverse effects like immunomodulatory and immunosuppressive effects, autophagy inhibition, steroid spanning effect, reversibility of drug resistance, antineoplastic and antiviral effects. Recently it has been proven that CAM successfully suppresses inflammatory cytokines responsible for cytokine release syndrome (CRS) and possesses an anti-SARS-CoV-2 effect. CAM leads to the suppression of the RdRp gene, resulting in the inhibition of SARS-CoV-2 ...