Can SARS-CoV-2 Transfer From Orofecal Route?

The development of effective public health measures requires complete information regarding the spread of disease from one individual to the other. Recent research suggests that SARS-CoV-2 can infect and shed from the human gastrointestinal tract that means policy should be improvised to lay more emphasis on strict personal hygiene and should suggest measures such as Chlorine-based disinfection of surfaces that are presumed to have SARS-CoV-2 activity.

Diarrhea was reported as the most common gastrointestinal symptom among the corona positive children and adults. This creates an urgency to go through the process that details the excretion of viruses in the feces. RT-PCR results report positive fecal samples for SARS-CoV-2 exposed individuals. Furthermore, Fecal PCR testing was found to be as accurate as respiratory specimen PCR.

Moreover, According, to an open evidence review, nearly 12% of the SARS-CoV-2 positive individuals show gastro-intestinal symptoms. Around 8 studies reported RNA shedding in the stool of 40.5 % corona positive individuals. 14 studies reported that the virus can be transmitted orofecally. While the observation and mechanistic evidence suggest that SARS-CoV-2 transferability from the human gastrointestinal tract.

Furthermore, it is suggested that there might be some gastric processes that may allow and facilitate the entry of viruses into the enterocytes. Thereby, considering the severity of transmission, healthcare policies should reform themselves that might prevent and undertake more precautions to prevent the transfer of disease.

Ref link: https://www.medrxiv.org/content/10.1101/2020.08.04.20168054v1