With a vigorous increase in vaccine trials around the globe, developing countries face a different challenge. Protestors in Africa gather around the University of the Witwatersrand in Johannesburg in South Africa on Wednesday reflecting long-running fears against the trials over testing drugs on people who do not understand the risks related to it even though the volunteers were given an explanation about the trial and possible risks. The CEO of the GAVI vaccine alliance, Seth Berkley, told the African Union that Anti-vaccine sentiment in Africa is one of the worst that was witnessed. It’s important that vaccines be tested in Africa to see how they perform in the local context, professor of vaccinology, Shabir Madhi, leader of the new COVID-19 vaccine trial in South Africa, told reporters and others in a webinar on Sunday. South Africa now has more than 151,000 confirmed coronavirus cases and Africa overall has more than 400,000 cases. As the pandemic picks up speed in Africa, health officials are urging that any vaccine be distributed equitably around the world.